Ok, in the original Toonstruck 2, Drew should be te same real guy like in Toonstruck 1. ok we could extract every animation of toonstruck 1 but this would be very difficult and we wouldn't have any chance to do new animations. So I think that we use a "Toon - Drew". In the Last Video of Toonstruck 1, Drew is pulled into the Toon world. He transforms into a Toon jsut before that and thats why i think a "Toon - Drew" would be logical to be in Toonstruck 2.
So i think we should use this image here as a reference: