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REGULATORS issued guidelines Tuesday for the establishment of a system to track overseas investments with the aim of preventing tax fraud Jalen Ramsey Jaguars Jersey , money laundering, illegal financing, and activities damaging the country’s reputation.


In a statement on its website, the National Development and Reform Commission (NDRC) warned that the government will record and tally instances of laws and regulations being broken in China or abroad, and offenders would be punished.


The plan Will Richardson Youth Jersey , jointly issued by 28 government departments, is part of efforts to regulate firms’ overseas investments and business activities as China’s influence in the global economy grows, especially through its Belt and Road Initiative.


In addition to illegal activities, the guidelines specifically say actions that “violate international conventions and resolutions of the United Nations, or that disrupt foreign economic cooperation DJ Chark Youth Jersey , adversely impact the Belt and Road Initiative, or harm China’s reputation” will be recorded.


The guidelines also focus on monitoring cross-border capital flows by insisting overseas deals are reasonable and disclosures are accurate.


China started to clamp down on capital outflows last year after its foreign currency reserves fell by nearly US$1 trillion. In August, the government laid out rules restricting investments in property, hotel, film Taven Bryan Youth Jersey , entertainment and sports. But the government also encouraged companies to support the nation’s Belt and Road Initiative.


Companies or individuals that break rules will be penalized in various ways. Authorities could reject their applications for overseas investments and foreign exchange purchases, restrict access to government subsidies and refuse to sell State land, the NDRC said.


Records of infractions will be available publicly through the government’s website www.creditchina.gov, the notice said. No timetable for implementing the system was given.


Authorities responsible for vetting applications to set up banks or acquire stakes in financial firms will be able to refer to the records before granting approval.


China’s non-financial outbound direct investment from January to October fell 40.9 percent year on year to US$86.31 billion, according to the Ministry of Commerce.(Shenzhen Daily-Agencies)


CHICAGO Logan Cooke Youth Jersey , Nov. 28 (Xinhua) -- Researchers at the University of Illinois (UI) are trying to use tiny drug-laden nanoparticles to seek and destroy cancer stem cells.


They used the nanoparticles to deliver niclosamide that targets a protein called CD44 only appearing on the surface of cancer stem cells, and found the cancer stem cells lost their stemlike properties after treatment with the niclosamide-bearing targeted nanoparticles, and are less able to cause the cancer to recur or metastasize.


The researchers also detected a significant decrease in overall cancer cell growth, both in the cell cultures and in the mice, according to a report released Monday on the UI website.


"I call them 'GPS-enabled nanoparticles Ronnie Harrison Youth Jersey ,' because they seek out only the cells that have cancer stem cell properties. Then they latch onto the cells and deliver the drug," said Dipanjan Pan, a UI professor of bioengineering. "To the best of our knowledge, this is the first demonstration of delivering cancer stem-cell-targeted therapy with a nanoparticle."


Cancer stem cells represent a tiny fraction of cells in a tumor, but it only takes one or two to seed a new tumor Dante Fowler Jr Youth Jersey , Pan said. The challenge for physicians and researchers is not only finding these cells, but treating them.


Previous study found that niclosamide works on a particular gene-regulation pathway in cancer stem cells. Niclosamide is on the World Health Organization's List of Essential Medicines, which is an index of the safest and most effective drugs in the world, and is a drug commonly prescribed to treat tapeworm infections.


"This work is important to future researchers working in the field of cancer stem cells," said postdoctoral researcher Santosh Misra Dawuane Smoot Youth Jersey , the first author of the study. "We described and confirmed the proteins and genes responsible for vital processes in these cells, and that is opening up new avenues to make better therapies."


UI researchers are now working to create a combination therapy that can deliver drugs for the primary cancer, such as traditional chemotherapies, as well as targeted agents that can treat cancer stem cells. They are also testing the nanoparticle drug-delivery system in large animal models to bring it a step closer to the clinic.


The study has been published in the journal Molecular Cancer Therapeutics.




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